| Объем | 100 мкл |
| Синонимы | Mediator complex subunit 1, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q15648 |
| Иммуноген | Synthesized peptide derived from internal of human MED1. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 |
| Примечание | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.<br/><br/>Drane P., Oncogene 15:3013-3024(1997).<br/>Yuan C.-X., Proc. Natl. Acad. Sci. U.S.A. 95:7939-7944(1998).<br/>Naeaer A.M., Nature 398:828-832(1999). |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling,Cancer,Metabolism |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from Jurkat cells, using MED1 antibody.
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Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using MED1 antibody.
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Наименование: MED1 Antibody.