MAP2K1 (Ab-291) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | ERK activator kinase 1, MAP kinase kinase 1, MAP2K1, MAPK/ERK kinase 1, MAPKK 1 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q02750 | | Иммуноген | Peptide sequence around aa. 289~293 (P-R-T-P-G) derived from Human MEK1. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:200 | | Примечание | Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases.<br/><br/>Kevin D. Burroughs, et,al. (2003) Mol. Cancer Res , 1: 312. <br/>Michael J. Piatelli, et,al. (2002) J. Biol. Chem , 277: 12144 - 12150. <br/>Margaret M. Morgan, et,al. (2001) J. Immunol , 167: 5708. <br/>Herbert Schramek, et,al. (2003) Am J Physiol Cell Physiol, , 285: C652 - C661. <br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. | | Области исследований | Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from HepG2 and PC12 cells using MEK1(Ab-291) Antibody.
 | Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using MEK1(Ab-291) Antibody(left) or the same antibody preincubated with blocking peptide(right).
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Наименование: MAP2K1 (Ab-291) Antibody.