Объем | 100 мкл |
Синонимы | JNKK, JNKK1, MAP2K4, MAPK/ERK kinase 4, kinase 4 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P45985 |
Иммуноген | Peptide sequence around aa. 78~82 (T-H-S-I-E) derived from Human SEK1/MKK4. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:200 |
Примечание | Dual specificity kinase that activates the JUN kinases MAPK8 (JNK1) and MAPK9 (JNK2) as well as MAPK14 (p38) but not MAPK1 (ERK2) or MAPK3 (ERK1).<br/><br/>Park HS, et al. (2002) J Biol Chem, 277(4): 2573-8. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
Области исследований | Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from PC12 and C2C12 cells using SEK1/MKK4(Ab-80) Antibody.
|
Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using SEK1/MKK4(Ab-80) Antibody(left) or the same antibody preincubated with blocking peptide(right).
|
| |