| Объем | 100 мкг |
| Синонимы | Mastermind-like protein 1 (Mam-1), MAML1, KIAA0200 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q92585 |
| Иммуноген | Recombinant Human Mastermind-like protein 1 protein (1-45AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA |
| Примечание | Acts as a transcriptional coactivator for NOTCH proteins. Has been shown to amplify NOTCH-induced transcription of HES1. Enhances phosphorylation and proteolytic turnover of the NOTCH intracellular domain in the nucleus through interaction with CDK8. Binds to CREBBP/CBP which promotes nucleosome acetylation at NOTCH enhancers and activates transcription. Induces phosphorylation and localization of CREBBP to nuclear foci. Plays a role in hematopoietic development by regulating NOTCH-mediated lymphoid cell fate decisions. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Biotin |
| Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | >95%, Protein G purified |
| Абревеатура | Mastermind-like protein 1 |
| Области исследований | Stem cells |
| Ссылка на страницу на сайте производителя | ссылка |
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Наименование: MAML1 Antibody, Biotin conjugated.