Объем | 100 мкл |
Синонимы | Endoplasmic reticulum mannosyl-oligosaccharide 1, 2-alpha-mannosidase, EC=3.2.1.113, ER alpha-1, 2-mannosidase |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q9UKM7 |
Иммуноген | Synthesized peptide derived from internal of human MAN1B1. |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Involved in glycoprotein quality control targeting of misfolded glycoproteins for degradation. It primarily trims a single alpha-1,2-linked mannose residue from Man9GlcNAc2 to produce Man8GlcNAc2, but at high enzyme concentrations, as found in the ER quality control compartment (ERQC), it further trims the carbohydrates to Man5-6GlcNAc2.<br/><br/>Tremblay L.O., Glycobiology 9:1073-1078(1999) [PubMed: 10521544].<br/>Gonzalez D.S., J. Biol. Chem. 274:21375-21386(1999) [PubMed: 10409699].<br/>Clark H.F., Genome Res. 13:2265-2270(2003) [PubMed: 12975309].<br/><br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Tags & Cell Markers |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from 3T3 cells, using MAN1B1 antibody.
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