Объем | 100 мкг |
Синонимы | Proto-oncogene Mas, MAS1, MAS |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P04201 |
Иммуноген | Recombinant Human Proto-oncogene Mas protein (285-325AA) |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB, IHC, IF, Recommended dilution: WB:1:500-1:2000, IHC:1:20-1:200, IF:1:50-1:200 |
Примечание | Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | >95%, Protein G purified |
Области исследований | Cancer, Cell biology, Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: MAS1 antibody at 2µg/ml
Lane 1: 293t cells
Lane 2: Colo320 cells
Lane 3: Hela cells
Lane 4: HepG2 cells
Lane 5: Mouse liver tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 37 kDa
Observed band size: 37 kDa
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Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA013505LA01HU at dilution of 1:100
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Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA013505LA01HU at dilution of 1:100
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Immunofluorescent analysis of Hela cells using CSB-PA013505LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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Immunofluorescent analysis of HepG2 cells using CSB-PA013505LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
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