Объем | 100 мкг |
Синонимы | Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3), MBD3 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | O95983 |
Иммуноген | Recombinant Human Methyl-CpG-binding domain protein 3 protein (79-209AA) |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB, IHC, Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200 |
Примечание | Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself (PubMed:12124384). Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides (PubMed:24307175). Recruits histone deacetylases and DNA methyltransferases. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | >95%, Protein G purified |
Абревеатура | Methyl-CpG-binding domain protein 3 |
Области исследований | Epigenetics and Nuclear Signaling |
Ссылка на страницу на сайте производителя | ссылка |
Western Blot
Positive WB detected in: Jurkat whole cell lysate, HEK293 whole cell lysate, Mouse brain tissue
All lanes: MBD3 antibody at 3µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 33, 30 kDa
Observed band size: 33 kDa
![](http://www.cusabio.cn/images/antibody/3/CSB-PA013532LA01HU-WB.jpg) |
Immunohistochemistry of paraffin-embedded human glioma using CSB-PA013532LA01HU at dilution of 1:100
![](http://www.cusabio.cn/images/antibody/3/CSB-PA013532LA01HU-IHC-1.jpg) |
Immunohistochemistry of paraffin-embedded human melanoma using CSB-PA013532LA01HU at dilution of 1:100
![](http://www.cusabio.cn/images/antibody/3/CSB-PA013532LA01HU-IHC-2.jpg) |
| |