Объем | 100 мкл |
Синонимы | minichromosome maintenance complex component 6 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q14566 |
Иммуноген | Fusion protein of human MCM6 |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB, IHC,ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:100-1:300 |
Примечание | The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 7 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. The phosphorylation of the complex by CDC2 kinase reduces the helicase activity, suggesting a role in the regulation of DNA replication. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Epigenetics and Nuclear Signaling |
Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA178919(MCM6 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ?200)
![](http://www.cusabio.cn/images/antibody/shgo/IHC/CSB-PA178919-P.jpg) |
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA178919(MCM6 Antibody) at dilution 1/60, on the right is treated with fusion protein. (Original magnification: ?200)
![](http://www.cusabio.cn/images/antibody/shgo/IHC/CSB-PA178919-1-P.jpg) |
Gel: 10%SDS-PAGE, Lysate: 40 ?g, Lane 1-5: 293T cells, A549 cells, Raji cells, K562 cells, NIH/3T3 cells, Primary antibody: CSB-PA178919(MCM6 Antibody) at dilution 1/433.3, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds
![](http://www.cusabio.cn/images/antibody/shgo/WB/CSB-PA178919.jpg) |
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