Объем | 100 мкг |
Синонимы | Mediator of RNA polymerase II transcription subunit 23 (Activator-recruited cofactor 130 kDa component) (ARC130) (Cofactor required for Sp1 transcriptional activation subunit 3) (CRSP complex subunit 3) (Mediator complex subunit 23) (Protein sur-2 homolog) (hSur-2) (Transcriptional coactivator CRSP130) (Vitamin D3 receptor-interacting protein complex 130 kDa component) (DRIP130), MED23, ARC130 CRSP3 DRIP130 KIAA1216 SUR2 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q9ULK4 |
Иммуноген | Recombinant Human Mediator of RNA polymerase II transcription subunit 23 protein (1014-1368AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA |
Примечание | Required for transcriptional activation subsequent to the assembly of the pre-initiation complex (By similarity). Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional pre-initiation complex with RNA polymerase II and the general transcription factors. Required for transcriptional activation by adenovirus E1A protein. Required for ELK1-dependent transcriptional activation in response to activated Ras signaling. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | FITC |
Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | >95%, Protein G purified |
Абревеатура | Mediator of RNA polymerase II transcription subunit 23 |
Области исследований | Epigenetics and Nuclear Signaling, Signal transduction |
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