| Объем | 100 мкл |
| Синонимы | EC 2.7.11.1, kinase Mnk1, Map kinase interacting kinase, MAP kinase signal-integrating kinase 1, MAP kinase-interacting serine/threonine kinase 1 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9BUB5 |
| Иммуноген | Synthesized non-phosphopeptide derived from human Mnk1 around the phosphorylation site of threonine 385 (L-P-T(p)-P-Q). |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB,WB:1:500-1:3000 |
| Примечание | May play a role in the response to environmental stress and cytokines. Appears to regulate translation by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.<br/><br/>Fukunaga R., EMBO J. 16:1921-1933(1997).<br/>Knauf U., Mol. Cell. Biol. 21:5500-5511(2001).<br/>O'Loghlen A., Exp. Cell Res. 299:343-355(2004).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from 3T3 cells, treated with PMA (125ng/ml, 30mins), using Mnk1 (Ab-385) antibody.
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Western blot analysis of extracts from HepG2 cells (Lane 2), K562 cells (Lane 3) and Jurket cells (Lane 4), using Mnk1 (Ab-385) antiobdy. The lane on the left is treated with systhesized peptide.
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Наименование: MKNK1 (Ab-385) Antibody.