MAPK6 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | Mitogen-activated protein kinase 6, EC 2.7.11.24, Extracellular signal-regulated kinase 3, ERK-3, MAP kinase isoform p97 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q16659 | Иммуноген | Synthesized peptide derived from internal of human p97 MAPK. | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB, IF,WB:1:500-1:3000, IF:1:100-1:500 | Примечание | Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle By similarity.<br/><br/>Zhu A.X., Mol. Cell. Biol. 14:8202-8211(1994).<br/>Meloche S., Oncogene 13:1575-1579(1996).<br/>The MGC Project Team, Genome Res. 14:2121-2127(2004) | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Области исследований | Signal transduction,Stem cells | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from K562 cells, using p97 MAPK antibody.
| Immunofluorescence analysis of MCF-7 cells, using p97 MAPK antibody.
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