Объем | 50 мкг |
Синонимы | Methyl-CpG-binding domain protein 3 (Methyl-CpG-binding protein MBD3), MBD3 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | O95983 |
Иммуноген | Recombinant Human Methyl-CpG-binding domain protein 3 protein (79-209AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA |
Примечание | Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself (PubMed:12124384). Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides (PubMed:24307175). Recruits histone deacetylases and DNA methyltransferases. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Biotin |
Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | >95%, Protein G purified |
Абревеатура | Methyl-CpG-binding domain protein 3 |
Области исследований | Epigenetics and Nuclear Signaling |
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