MBTPS1 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | Endopeptidase S1P, KIAA0091, MBTP1, MBTPS1, membrane-bound transcription factor peptidase | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q14703 | | Иммуноген | Synthesized peptide derived from C-terminal of human MBTPS1. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB,WB:1:500-1:3000 | | Примечание | Serine protease that catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs). Other known substrates are BDNF, GNPTAB and ATF6. Cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4. Cleaves known substrates after Arg-Ser-Val-Leu (SERBP-2), Arg-His-Leu-Leu (ATF6), Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu. Mediates the protein cleavage of GNPTAB into subunit alpha and beta, thereby participating in biogenesis of lysosomes.<br/><br/>Nakajima T., J. Hum. Genet. 45:212-217(2000).<br/>Nagase T., DNA Res. 2:37-43(1995).<br/>Bechtel S., BMC Genomics 8:399-399(2007).<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Epigenetics and Nuclear Signaling,Cell biology,Metabolism,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from Jurkat/COLO205 cells, using MBTPS1 antibody.
 | | | |
Информация для заказа |
Наименование: MBTPS1 Antibody.