| Объем | 100 мкл |
| Синонимы | Thyroid hormone receptor-associated protein complex 230 kDa component, Trap230, Activator-recruited cofactor 240 kDa component, ARC240, CAG repeat protein 45 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q93074 |
| Иммуноген | Synthesized peptide derived from internal of human MED12. |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, IHC,IHC:1:50-1:100 |
| Примечание | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway.<br/><br/>Ito M., Mol. Cell 3:361-370(1999).<br/>Nagase T., DNA Res. 3:17-24(1996).<br/>Philibert R.A., Mol. Psychiatry 3:303-309(1998).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Epigenetics and Nuclear Signaling |
| Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using MED12 antibody.
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Наименование: MED12 Antibody.