PAK3 Antibody, FITC conjugatedСпецификацияОбъем | 100 мкг | Синонимы | Serine/threonine-protein kinase PAK 3 (EC 2.7.11.1) (Beta-PAK) (Oligophrenin-3) (p21-activated kinase 3) (PAK-3), PAK3, OPHN3 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | O75914 | Иммуноген | Recombinant Human Serine/threonine-protein kinase PAK 3 protein (70-190AA) | Источник | Rabbit | Видовая специфичность | Human | Применение | ELISA | Примечание | Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, or cell cycle regulation. Plays a role in dendrite spine morphogenesis as well as synapse formation and plasticity. Acts as downstream effector of the small GTPases CDC42 and RAC1. Activation by the binding of active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates MAPK4 and MAPK6 and activates the downstream target MAPKAPK5, a regulator of F-actin polymerization and cell migration. Additionally, phosphorylates TNNI3/troponin I to modulate calcium sensitivity and relaxation kinetics of thin myofilaments. May also be involved in early neuronal development. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | FITC | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | >95%, Protein G purified | Абревеатура | Serine/threonine-protein kinase PAK 3 | Области исследований | Neuroscience, Signal transduction | Ссылка на страницу на сайте производителя | ссылка | | |
Информация для заказаОбласть использования: | Производство: | Cusabio | Метод: | Антитела | Объем: | 100 мкг | Кат. номер: | CSB-PA017407LC01HU | Цена (с НДС 20%): | по запросу | В корзину | Наименование: PAK3 Antibody, FITC conjugated. Примечание: дополнительная информация (на английском языке). |
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