PC AntibodyСпецификацияОбъем | 100 мкл | Синонимы | Pyruvate carboxylase | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P11498 | Иммуноген | Fusion protein of human PC | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB,ELISA:1:1000-1:2000, WB:1:200-1:1000 | Примечание | This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Cancer,Metabolism,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | Gel: 8%SDS-PAGE, Lysate: 40 ?g, Lane: Hela cells, Primary antibody: CSB-PA281482(PC Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
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