Объем | 50 мкл |
Синонимы | Meningioma expressed antigen 5 (hyaluronidase) |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | O60502 |
Иммуноген | Fusion protein of human MGEA5 |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB, IHC,ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:25-1:100 |
Примечание | The dynamic modification of cytoplasmic and nuclear proteins by O-linked N-acetylglucosamine (O-GlcNAc) addition and removal on serine and threonine residues is catalyzed by OGT, which adds O-GlcNAc, and MGEA5, a glycosidase that removes O-GlcNAc modifications. Cleaves GlcNAc but not GalNAc from glycopeptides. Can use p-nitrophenyl-beta-GlcNAc as substrate but not p-nitrophenyl-beta-GalNAc or p-nitrophenyl-alpha-GlcNAc. Possesses hyaluronidase activity. Acetylates 'Lys-8' of histone H4 and 'Lys-14' of histone H3. Shows highest expression in the brain, placenta and pancreas. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen affinity purification |
Области исследований | Cancer,Immunology,Metabolism,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA797342(MGEA5 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ?200)
![](http://www.cusabio.cn/images/antibody/shgo/IHC/CSB-PA797342-P.jpg) |
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA797342(MGEA5 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ?200)
![](http://www.cusabio.cn/images/antibody/shgo/IHC/CSB-PA797342-1-P.jpg) |
Gel: 8%SDS-PAGE, Lysate: 40 ?g, Lane: Human fetal liver tissue, Primary antibody: CSB-PA797342(MGEA5 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
![](http://www.cusabio.cn/images/antibody/shgo/WB/CSB-PA797342.jpg) |
| |