PDGFB AntibodyСпецификацияОбъем | 100 мкл | Синонимы | PDGF2, ONCOGENE SIS, PDGF B CHAIN, PLATELET-DERIVED GROWTH FACTOR B CHAIN, SIMIAN SARCOMA VIRAL ONCOGENE HOMOLOG | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P01127 | Иммуноген | Synthesized peptide derived from human PDGFB. | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB,WB:1:500-1:3000 | Примечание | Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal proliferation and recruitment of pericytes and vascular smooth muscle cells in the central nervous system, skin, lung, heart and placenta. Required for normal blood vessel development, and for normal development of kidney glomeruli. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA By similarity.<br/><br/>Li Fang, Arterioscler. Thromb. Vasc. Biol., Apr 2004, 24: 787 - 792. <br/>EJ Battegay, J. Cell Biol., May 1994, 125: 917. <br/>RA Seifert, J. Biol. Chem., Feb 1993, 268: 4473 - 4480. <br/>Jason Liu, Am J Physiol Lung Cell Mol Physiol, May 1998, 274: 702.<br/><br/> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Области исследований | Cancer,Cardiovascular,Developmental biology,Metabolism,Signal transduction | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from NIH/3T3 cells, using PDGFB antibody.
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