MNDA AntibodyСпецификация| Объем | 100 мкл | | Синонимы | myeloid cell nuclear differentiation antigen, PYHIN3, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P41218 | | Иммуноген | Synthesized peptide derived from C-terminal of human MNDA. | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA, WB,WB:1:500-1:3000 | | Примечание | The myeloid cell nuclear differentiation antigen (MNDA) is detected only in nuclei of cells of the granulocyte-monocyte lineage. A 200-amino acid region of human MNDA is strikingly similar to a region in the proteins encoded by a family of interferon-inducible mouse genes, designated Ifi-201, Ifi-202, and Ifi-203, that are not regulated in a cell- or tissue-specific fashion. The 1.8-kb MNDA mRNA, which contains an interferon-stimulated response element in the 5-prime untranslated region, was significantly upregulated in human monocytes exposed to interferon alpha. MNDA is located within 2,200 kb of FCER1A, APCS, CRP, and SPTA1. In its pattern of expression and/or regulation, MNDA resembles IFI16, suggesting that these genes participate in blood cell-specific responses to interferons.<br/><br/>Briggs J.A., J. Cell. Biochem. 49:82-92(1992).<br/>The MGC Project Team, Genome Res. 14:2121-2127(2004).<br/>Burrus G.R., J. Cell. Biochem. 48:190-202(1992).<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Immunology,Stem cells | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from LOVO cells, using MNDA antibody.
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Наименование: MNDA Antibody.