Phospho-BCAR1 (Tyr410) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | BCAR1, CRKAS, CRK-ASSOCIATED SUBSTRATE, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P56945 | | Иммуноген | Peptide sequence around phosphorylation site of tyrosine 410(G-V-Y(p)-A-V) derived from Human p130 Cas . | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:100 | | Примечание | <p>Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.<br/><br/>Katarzyna Modzelewska, J. Biol. Chem., Dec 2006, 281: 37527 - 37535.<br />Kevin Ogden, Am J Physiol Heart Circ Physiol, Dec 2006, 291: H2857 - H2863.<br />Sangkil Nam, Cancer Res., Oct 2005, 65: 9185 - 9189.<br />Norikazu Yamana, Mol. Cell. Biol., Sep 2006, 26: 6844 - 6</p> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. | | Абревеатура | Phospho-Tyr410 | | Области исследований | Cancer,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from K562 cells (Lane 2) and 3T3 cells (Lane 3), using P130 Cas(Phospho-Tyr410) Antibody. The lane on the left is treated with antigen-specific peptide.
 | Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using p130 Cas (Phospho-Tyr410) antibody (left)or the same antibody preincubated with blocking peptide (right).
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Информация для заказа| Область использования: | Производство: | Cusabio | | Метод: | Антитела | | Объем: | 100 мкл | | Кат. номер: | CSB-PA975216 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: Phospho-BCAR1 (Tyr410) Antibody.
Примечание: дополнительная информация (на английском языке). |
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