Объем | 100 мкл |
Синонимы | l10mt, mgc17973, mitochondrial ribosomal protein l10, mrp-l10, mrp-l8 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q7Z7H8 |
Иммуноген | Synthesized peptide derived from internal of human MRPL10. |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB,WB:1:500-1:3000 |
Примечание | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Sequence analysis identified three transcript variants that encode two different isoforms. A pseudogene corresponding to this gene is found on chromosome 5q.<br/><br/>The MGC Project Team, Genome Res. 14:2121-2127(2004).<br/>Kenmochi N., Genomics 77:65-70(2001).<br/>Koc E.C., J. Biol. Chem. 276:43958-43969(2001) |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Epigenetics and Nuclear Signaling |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HepG2 cells, COLO cells and 293 cells, using MRPL10 antibody.
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