NCKAP1 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | NCK-associated protein 1 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q9Y2A7 | | Иммуноген | Synthetic peptide of human NCKAP1 | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, IHC,ELISA:1:1000-1:2000, IHC:1:25-1:100 | | Примечание | NAP125, also known as NCKAP1 (NCK-associated protein 1), p125Nap1 or membrane-associated protein HEM-2, is a 1,128 amino acid single pass membrane protein that exists as two alternatively spliced isoforms and belongs to the HEM-1/HEM-2 family. While widely expressed, NAP125 is found at highest levels in heart, brain and skeletal muscle where it regulates Rac-dependent actin remodeling as part of a lamellipodial complex with WAVE2, Abi-1 and CYFIP1. NAP125 localizes to the cytoplasmic side of lamellipodium membrane and is encoded by a gene that maps to human chromosome 2q32.1 and mouse chromosome 2 C3. NAP125 expression is markedly reduced in Alzheimer disease (AD)-affected brains, suggesting a possible role in the disease. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antigen affinity purification | | Области исследований | Neuroscience,Cancer,Cell biology,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA982423(NCKAP1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ?200)
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Наименование: NCKAP1 Antibody.