MRPS12 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | 28S ribosomal protein S12 mitochondrial, S12mt, MRP-S12, MT-RPS12, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | O15235 | | Иммуноген | Synthesized peptide derived from internal of human MRPS12. | | Источник | Rabbit | | Видовая специфичность | Human | | Применение | ELISA, WB,WB:1:500-1:3000 | | Примечание | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S12P family. The encoded protein is a key component of the ribosomal small subunit and controls the decoding fidelity and susceptibility to aminoglycoside antibiotics. The gene for mitochondrial seryl-tRNA synthetase is located upstream and adjacent to this gene, and both genes are possible candidates for the autosomal dominant deafness gene (DFNA4). Splice variants that differ in the 5' UTR have been found for this gene, all three variants encode the same protein.<br/><br/>Shah Z.H., Gene 204:55-62(1997).<br/>Johnson D.F., Genomics 52:363-368(1998).<br/>Ebert L., Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Epigenetics and Nuclear Signaling,Tags & Cell Markers | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from K562 cells, using MRPS12 antibody.
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Наименование: MRPS12 Antibody.