Объем | 100 мкл |
Синонимы | Tyrosine kinase-type cell surface receptor HER3 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P21860 |
Иммуноген | Peptide sequence around phosphorylation site of tyrosine 1328 (P-D-Y(p)-W-H) derived from Human Her3/ErbB3. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB, IHC, IF,WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200 |
Примечание | Binds and is activated by neuregulins and NTAK.<br/><br/>Holbro, T. et al. (2003) Proc. Natl. Acad. Sci. USA 100, 8933-8938.<br/>Kobayashi, M. et al. (2003) Oncogene 22, 1294-1301. <br/>Kim, H.H. et al. (1994) J. Biol. Chem. 269, 24747-24755.<br/>Yarden, Y. and Sliwkowski, M.X. (2001) Nature Rev. Mol. Cell. Biol. 2, 127-137.<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
Абревеатура | Phospho-Tyr1328 |
Области исследований | Cancer,Tags & Cell Markers,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from A431 cells untreated or treated with EGF using Her3/ErbB3(phospho-Tyr1328) Antibody.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Her3/ErbB3(Phospho-Tyr1328) Antibody(left) or the same antibody preincubated with blocking peptide(right).
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Immunofluorescence staining of methanol-fixed MCF7 cells using Her3/ErbB3(phospho-Tyr1328) Antibody.
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