NFE2L2 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | HEBP1, NF-E2 related factor 2, NF2L2, NFE2-related factor 2, NFE2L2 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q16236 | Иммуноген | Synthesized peptide derived from human NRF2. | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB, IHC, IF,WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500 | Примечание | Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.<br/><br/>Rajesh K. Thimmulappa, J. Clin. Invest., Apr 2006, 116: 984 - 995. <br/>Sara B. Cullinan, Mol. Cell. Biol., Oct 2003, 23: 7198 - 7209. <br/>Tirumalai Rangasamy, J. Exp. Med., Jul 2005, 202: 47 - 59. <br/>Wenge Li, J. Biol. Chem., Aug 2005, 280: 28430 - 28438. <br/><br/> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Области исследований | Epigenetics and Nuclear Signaling,Cardiovascular,Cell biology,Metabolism | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from HuvEc cells, using NRF2 antibody.
 | Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using NRF2 antibody.
 | Immunofluorescence analysis of HuvEc cells, using NRF2 antibody.
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