NKX3-1 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | Homeobox protein Nkx-3.1, NKX31, NKX3A, | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q99801 | Иммуноген | Synthesized peptide derived from N-terminal of human NKX3. | Источник | Rabbit | Видовая специфичность | Human | Применение | ELISA, IHC,IHC:1:50-1:100 | Примечание | Transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. Plays an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.<br/><br/>Cai Bowen, Cancer Res., Jan 2007, 67: 455 - 464. <br/>Xiang Li, Mol. Cell. Biol., Apr 2006, 26: 3008 - 3017. <br/>Ekatherine Asatiani, Cancer Res., Feb 2005, 65: 1164 - 1173. <br/>Carlise R. Bethel, Cancer Res., Nov 2006, 66: 10683 - 10690. <br/> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Области исследований | Epigenetics and Nuclear Signaling | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using NKX3.1 antibody.
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