Объем | 100 мкл |
Синонимы | GLR1, GLUH1, GRIA1, GluR-1, GluR-A |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P42261 |
Иммуноген | Peptide sequence around phosphorylation site of serine 836 (S-E-Sp-K-R) derived from Human GluR1 |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB,WB:1:500-1:1000 |
Примечание | Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of a-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.<br/><br/>Emamian ES, et al. (2004) J Neurosci. 24(7): 1561-4<br/>Palmer, C.L. et al. (2005) Pharmacol. Rev. 57, 253-277. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
Абревеатура | Phospho-Ser836 |
Области исследований | Neuroscience |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from mouse brain and using GluR1(phospho-Ser836) Antibody.
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