| Объем | 100 мкл |
| Синонимы | NACHT, LRR and PYD domains-containing protein 2 (Nucleotide-binding site protein 1) (PYRIN domain and NACHT domain-containing protein 1) (PYRIN-containing APAF1-like protein 2), NLRP2, NALP2 NBS1 PAN1 PYPAF2 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9NX02 |
| Иммуноген | Recombinant Human NACHT, LRR and PYD domains-containing protein 2 protein (1-220AA) |
| Источник | Rabbit |
| Видовая специфичность | Human |
| Применение | ELISA, WB, IHC, Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200 |
| Примечание | Suppresses TNF- and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature proinflammatory cytokine IL1B. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen Affinity Purified |
| Области исследований | Cell biology |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: NLRP2 antibody at 12µg/ml + A431 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 121, 119, 97, 118 kDa
Observed band size: 121 kDa
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Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA865163ESR1HU at dilution of 1:100
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Наименование: NLRP2 Antibody.