Phospho-MEF2A (Thr319) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | MEF2, Serum response factor-like protein 1, | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q02078 | | Иммуноген | Peptide sequence around phosphorylation site of Thr319 (V-T-T(p)-P-S) derived from Human MEF2A. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, IF,IF:1:100-1:200 | | Примечание | The process of differentiation from mesodermal precursor cells to myoblasts has led to the discovery of a variety of tissue-specific factors that regulate muscle gene expression. The myogenic basic helix-loop-helix proteins, including myoD (MIM 159970), myogenin (MIM 159980), MYF5 (MIM 159990), and MRF4 (MIM 159991) are one class of identified factors. A second family of DNA binding regulatory proteins is the myocyte-specific enhancer factor-2 (MEF2) family. Each of these proteins binds to the MEF2 target DNA sequence present in the regulatory regions of many, if not all, muscle-specific genes. The MEF2 genes are members of the MADS gene family (named for the yeast mating type-specific transcription factor MCM1, the plant homeotic genes 'agamous' and 'deficiens' and the human serum response factor SRF (MIM 600589)), a family that also includes several homeotic genes and other transcription factors, all of which share a conserved DNA-binding domain<br/><br/>Shore, P. et al. (1995) Eur. J. Biochem. 229, 1-13<br/>Martin, J.F. et al. (1994) Mol. Cell. Biol. 14, 1647-1656<br/>Yu, Y.T. et al. (1992) Genes Dev. 6, 1783-1798<br/>Zhao, M. et al. (1999) Mol. Cell. Biol. 19, 21-30<br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. | | Абревеатура | Phospho-Thr319 | | Области исследований | Epigenetics and Nuclear Signaling,Neuroscience,Cardiovascular | | Ссылка на страницу на сайте производителя | ссылка | Immunofluorescence staining of methanol-fixed Hela cells using MEF2A(Phospho-Thr319) Antibody.
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Информация для заказа| Область использования: | Производство: | Cusabio | | Метод: | Антитела | | Объем: | 100 мкл | | Кат. номер: | CSB-PA956856 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: Phospho-MEF2A (Thr319) Antibody.
Примечание: дополнительная информация (на английском языке). |
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