NUB1 AntibodyСпецификацияОбъем | 100 мкл | Синонимы | NEDD8 ultimate buster-1, NUB1, NY-REN-18 antigen, | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q9Y5A7 | Иммуноген | Synthesized peptide derived from C-terminal of human NYREN18. | Источник | Rabbit | Видовая специфичность | Human, Mouse | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | Примечание | Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8, UBD, and their conjugates to the proteasome for degradation. Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2.<br/><br/>Sarah M. Mense, Toxicol. Sci., Sep 2006, 93: 125 - 135.<br/>Gunter Schmidtke, J. Biol. Chem., Jul 2006, 281: 20045 - 20054.s<br/>Kunikazu Tanji, Am. J. Pathol., Aug 2006, 169: 553 - 565.<br/>Miguel Ramalho-Santos, Science, Oct 2002, 298: 597. <br/> | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Области исследований | Cell biology | Ссылка на страницу на сайте производителя | ссылка | Immunohistochemistry analysis of paraffin-embedded human tonsil tissue using NYREN18 antibody.
| Western blot analysis of extracts from COS7 cells, using NYREN18 antibody.
| Western blot analysis of extracts from HuvEc cells (Lane 2) and JK cells (Lane 3), using NYREN18 antiobdy. The lane on the left is treated with synthesized peptide.
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