Объем | 100 мкл |
Синонимы | KS6A1, MAPKAP-K1a, RPS6KA1, RSK1, S6K-alpha 1 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q15418 |
Иммуноген | Peptide sequence around phosphorylation site of threonine 348 (S-R-T(p)-P-R) derived from Human p90RSK. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB, IHC, IF,WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200 |
Примечание | Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB.<br/><br/>Silverman E, et al. Mol Cell Biol. 2004 Dec, 24(24): 10573-10583.<br/>Andrew D, et al. Biochem J. 2006 February 1, 393(Pt 3): 715 |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
Абревеатура | Phospho-Thr348 |
Области исследований | Epigenetics and Nuclear Signaling,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from Hela cells untreated or treated with UV using p90RSK(Phospho-Thr348) Antibody.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using p90RSK(Phospho-Thr348) Antibody(left) or the same antibody preincubated with blocking peptide(right).
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Immunofluorescence staining of methanol-fixed Hela cells using p90RSK(Phospho-Thr348) Antibody.
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