Phospho-RUNX1 (Ser276) AntibodyСпецификацияОбъем | 100 мкл | Синонимы | CBFA2, EVI-1, AMLCR1, PEBP2aB, AML1-EVI-1 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q01196 | Иммуноген | Peptide sequence around phosphorylation site of serine 276(P-I-S(p)-P-G) derived from Human AML1. | Источник | Rabbit | Видовая специфичность | Human, Mouse, Rat | Применение | ELISA, WB,WB:1:500-1:1000 | Примечание | CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. The alpha subunit binds DNA and appears to have a role in the development of normal hematopoiesis. Isoform AML-1L interferes with the transactivation activity of RUNX1. Acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the mouse BLK promoter. Inhibits KAT6B-dependent transcriptional activation. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | Форма | liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. | Абревеатура | Phospho-Ser276 | Области исследований | Epigenetics and Nuclear Signaling,Neuroscience,Cancer,Developmental biology,Stem cells | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from JK cells using AML1 (Phospho-Ser276) Antibody.The lane on the left is treated with the antigen-specific peptide.
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Информация для заказаОбласть использования: | Производство: | Cusabio | Метод: | Антитела | Объем: | 100 мкл | Кат. номер: | CSB-PA570589 | Цена (с НДС 20%): | по запросу | В корзину | Наименование: Phospho-RUNX1 (Ser276) Antibody. Примечание: дополнительная информация (на английском языке). |
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