NEK4 AntibodyСпецификацияОбъем | 50 мкл | Синонимы | NIMA-related kinase 4 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | P51957 | Иммуноген | Synthetic peptide of human NEK4 | Источник | Rabbit | Видовая специфичность | Human, Mouse | Применение | ELISA, IHC,ELISA:1:2000-1:5000, IHC:1:25-1:100 | Примечание | NIMA was originally shown in Aspergillus nidulans to be necessary for entry into mitosis. NIMA-related mammalian proteins have since been identified as Nek1, Nek2, Nek3 and Nek4 (also designated STK2 or NRK2). High expression of Nek1 is seen in male and female germ cell lines of mouse. Nek2 is the closest known mammalian relative to NIMA. Like NIMA, Nek2 expression peaks at the G2 to M phase transition. Nek3 is a predominantly cytoplasmic enzyme that was detectable in all organs studied. Levels of Nek3 seem to remain unchanged throughout the cell cycle, but appear to be elevated in G0-arrested, quiescent fibroblasts. In developing testicular germ cells, differential patterns of expression were seen for Nek1, Nek2 and Nek4, indicating possible overlapping, but non-identical functions. | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Non-conjugated | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | Antigen affinity purification | Области исследований | Signal transduction | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA225643(NEK4 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ?200)
| The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA225643(NEK4 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ?200)
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