Объем | 100 мкл |
Синонимы | Signal transducer and activator of transcription 5B, STA5B, STAT5, transcription factor STAT5B, |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | P42230/P42232 |
Иммуноген | Peptide sequence around phosphorylation site of serine725/730(A-P-S(p)-P-V) derived from Human STAT5A/B. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, WB,WB:1:500-1:1000 |
Примечание | <p>Carries out a dual function: signal transduction and activation of transcription. Binds to the GAS element and activates PRL-induced transcription. <br /><br />Ross JA, et al. (2010) J Biol Chem 285, 3582-91 <br />Uddin S, et al. (2003) Biochem Biophys Res Commun 308, 325-30<br />Xue HH, et al. (2002) Int Immunol 14, 1263-71</p> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
Абревеатура | Phospho-Ser725/730 |
Области исследований | Epigenetics and Nuclear Signaling,Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from Jurkat cells treated with EGF using Phospho-STAT5A/B (Ser725/730) antibody.The lane on the right is treated with the antigen-specific peptide.
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