Phospho-ZAP70 (Tyr319) AntibodyСпецификация| Объем | 100 мкл | | Синонимы | SRK, STD, TZK, STCD, ZAP-70 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | P43403 | | Иммуноген | Peptide sequence around phosphorylation site of tyrosine 319 (S-P-Y(p)-S-D) derived from Human Zap-70. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC, IF,WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200 | | Примечание | <p>Plays a role in T-cell development and lymphocyte activation. Essential for TCR-mediated IL-2 production. Isoform 1 induces TCR-mediated signal transduction, isoform 2 does not. <br /><br />Salomon AR, et al. (2003) Proc Natl Acad Sci U S A, 100(2): 443-448 <br />Ku GM, et al. (2001) EMBO J, 20(3): 457-465 <br />Tang J, et al. (1999) Proc Natl Acad Sci U S A, 96(17): 9775-9780 <br />Zhao Q, et al. (1996) Mol Cell Biol, 16(12): 6765-6774 <br />Williams BL, et al. (1999) EMBO J, 18(7): 1832-1844 <br />Adjali O, et al. (2005) J Clin Invest, 115(8): 2287-2295.</p> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. | | Абревеатура | Phospho-Tyr319 | | Области исследований | Tags & Cell Markers,Immunology,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from Jurkat cells using Zap-70(Phospho-Tyr319) Antibody(Lane 2) and the same antibody preincubated with blocking peptide(Lane1).
 | Immunofluorescence staining of methanol-fixed Hela cells using Zap-70(Phospho-Tyr319) Antibody.
 | Western blot analysis of extracts from HL60 cells, treated with calf intestinal phosphatase (CIP), using Zap-70 (Phospho-Tyr319) Antibody.
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Информация для заказа| Область использования: | Производство: | Cusabio | | Метод: | Антитела | | Объем: | 100 мкл | | Кат. номер: | CSB-PA969675 | | Цена (с НДС 20%): | по запросу | В корзину  |  Наименование: Phospho-ZAP70 (Tyr319) Antibody.
Примечание: дополнительная информация (на английском языке). |
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