Объем | 100 мкл |
Синонимы | Polyadenylate-binding protein-interacting protein 1 (PABP-interacting protein 1) (PAIP-1) (Poly(A)-binding protein-interacting protein 1), PAIP1 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q9H074 |
Иммуноген | Recombinant Human Polyadenylate-binding protein-interacting protein 1 protein (1-260AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB, Recommended dilution: WB:1:200-1:1000 |
Примечание | Acts as a coactivator in the regulation of translation initiation of poly(A)-containing mRNAs. Its stimulatory activity on translation is mediated via its action on PABPC1. Competes with PAIP2 for binding to PABPC1. Its association with EIF4A and PABPC1 may potentiate contacts between mRNA termini. May also be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antigen Affinity Purified |
Области исследований | Epigenetics and Nuclear Signaling |
Ссылка на страницу на сайте производителя | ссылка |
Western blot
All lanes: PAIP1 antibody at 8µg/ml
Lane 1: Hela whole cell lysate
Lane 2: PC-3 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 54, 46, 43 kDa
Observed band size: 54 kDa
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