| Объем | 50 мкл |
| Синонимы | nuclear receptor binding SET domain protein 1 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q96L73 |
| Иммуноген | Synthetic peptide of human NSD1 |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, IHC,ELISA:1:2000-1:5000, IHC:1:20-1:100 |
| Примечание | This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene. |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Форма | Liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antigen affinity purification |
| Области исследований | Epigenetics and Nuclear Signaling |
| Ссылка на страницу на сайте производителя | ссылка |
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA240911(NSD1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ?200)The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA240911(NSD1 Antibody) at dilution 1/25, on the right is treated with synthetic peptide. (Original magnification: ?200)
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Наименование: NSD1 Antibody.