PLEKHG6 AntibodyСпецификация| Объем | 50 мкл | | Синонимы | pleckstrin homology domain containing, family G (with RhoGef domain) member 6 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q3KR16 | | Иммуноген | Fusion protein of human PLEKHG6 | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, WB, IHC,ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:25-1:100 | | Примечание | PLEKHG6 functions as a guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. It activates RHOG but not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving MyoGEF, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antigen affinity purification | | Области исследований | Cancer,Cell biology,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA212466(PLEKHG6 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ?200)
 | The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using CSB-PA212466(PLEKHG6 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ?200)
 | Gel: 6%SDS-PAGE, Lysate: 40 ?g, Lane: 293T cells, Primary antibody: CSB-PA212466(PLEKHG6 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
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Наименование: PLEKHG6 Antibody.