OAS3 Antibody, Biotin conjugatedСпецификацияОбъем | 100 мкг | Синонимы | 2'-5'-oligoadenylate synthase 3 ((2-5')oligo(A) synthase 3) (2-5A synthase 3) (EC 2.7.7.84) (p100 OAS) (p100OAS), OAS3 | Клональность | Polyclonal Antibody | Организм | Human | uniprot | Q9Y6K5 | Иммуноген | Recombinant Human 2'-5'-oligoadenylate synthase 3 protein (424-565AA) | Источник | Rabbit | Видовая специфичность | Human | Применение | ELISA | Примечание | Interferon-induced, dsRNA-activated antiviral enzyme which plays a critical role in cellular innate antiviral response. In addition, it may also play a role in other cellular processes such as apoptosis, cell growth, differentiation and gene regulation. Synthesizes preferentially dimers of 2'-5'-oligoadenylates (2-5A) from ATP which then bind to the inactive monomeric form of ribonuclease L (RNase L) leading to its dimerization and subsequent activation. Activation of RNase L leads to degradation of cellular as well as viral RNA, resulting in the inhibition of protein synthesis, thus terminating viral replication. Can mediate the antiviral effect via the classical RNase L-dependent pathway or an alternative antiviral pathway independent of RNase L. Displays antiviral activity against Chikungunya virus (CHIKV), Dengue virus, Sindbis virus (SINV) and Semliki forest virus (SFV). | Клональность1 | Polyclonal | Изотип | IgG | Коньюгат | Biotin | Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 | Форма | Liquid | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | Метод очистки | >95%, Protein G purified | Абревеатура | 2'-5'-oligoadenylate synthase 3 | Области исследований | Epigenetics and Nuclear Signaling, Immunology | Ссылка на страницу на сайте производителя | ссылка | | |
Информация для заказаОбласть использования: | Производство: | Cusabio | Метод: | Антитела | Объем: | 100 мкг | Кат. номер: | CSB-PA897591LD01HU | Цена (с НДС 20%): | по запросу | В корзину | Наименование: OAS3 Antibody, Biotin conjugated. Примечание: дополнительная информация (на английском языке). |
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