| Объем | 100 мкл |
| Синонимы | Pleckstrin homology-like domain family A member 3, TDAG51/Ipl homolog 1, PHLDA3, TIH1, |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | Q9Y5J5 |
| Иммуноген | Synthesized peptide derived from internal of human PHLDA3. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 |
| Примечание | p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to the cellular membrane and activation. Contributes to p53/TP53-dependent apoptosis by repressing AKT1 activity. Its direct transcription regulation by p53/TP53 may explain how p53/TP53 can negatively regulate AKT1. May act as a tumor suppressor.<br/><br/>Frank D., Mamm. Genome 10:1150-1159(1999).<br/>Ota T., Nat. Genet. 36:40-45(2004).<br/>The MGC Project Team, Genome Res. 14:2121-2127(2004).<br/> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Области исследований | Cell biology |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from JK cells, using PHLDA3 antiobdy.
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Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using PHLDA3 antibody.
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Наименование: PHLDA3 Antibody.