| Объем | 100 мкл |
| Синонимы | ATF1, Activating transcription factor 1, Cyclic-AMP-dependent transcription factor ATF-1, TCR-ATF1, TREB36 protein |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P18846 |
| Иммуноген | Peptide sequence around phosphorylation site of serine 63(R-P-S(p)-Y-R) derived from Human ATF1 . |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB,WB:1:500-1:1000 |
| Примечание | <p>This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation. <br/><br/>Mackenzie KF, et al. (2013) J Immunol 190, 565-77 <br />Dickinson RJ, et al. (2011) J Biol Chem 286, 38018-26 <br />Wang J, Zhou JY, Wu GS (2011) J Biol Chem 286, 22384-92</p> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Абревеатура | Phospho-Ser63 |
| Области исследований | Epigenetics and Nuclear Signaling |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HT29 cells treated with Insulin using Phospho-ATF1 (Ser63) antibody.The lane on the right is treated with the antigen-specific peptide.
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Наименование: Phospho-ATF1 (Ser63) Antibody.