Объем | 100 мкл |
Синонимы | PDZ domain-containing protein 2, PDZ domain-containing protein 3, Activated in prostate cancer protein, Processed PDZ domain-containing protein 2, PDZD2 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | O15018 |
Иммуноген | Synthesized peptide derived from internal of human PDZD2. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, IHC, IF,IHC:1:50-1:100, IF:1:100-1:500 |
Примечание | Proteins containing PDZ domains have been shown frequently to bind the C-termini of transmembrane receptors or ion channels. They have also been shown to bind to other PDZ domain proteins and could possibly be involved in intracellular signalling. The protein encoded by this gene contains six PDZ domains and shares sequence similarity with pro-interleukin-16 (pro-IL-16). Like pro-IL-16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis.<br/><br/>Chaib H., Cancer Res. 61:2390-2394(2001).<br/>Nagase T., DNA Res. 4:141-150(1997).<br/> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Области исследований | Neuroscience |
Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemistry analysis of paraffin-embedded human prostate carcinoma tissue, using PDZD2 antibody.
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Immunofluorescence analysis of HepG2 cells, using PDZD2 antibody.
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