PRKG2 AntibodyСпецификация| Объем | 100 мкл | | Синонимы | protein kinase, cGMP-dependent, type II | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q13237 | | Иммуноген | Synthetic peptide of human PRKG2 | | Источник | Rabbit | | Видовая специфичность | Human, Mouse, Rat | | Применение | ELISA, WB, IHC,ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:25-1:100 | | Примечание | cGKII (cGMP-dependent protein kinase type II) is a major receptor of intracellular cGMP and mediates a plethora of physiological responses. cGKII contains a conserved leucine zipper motif at the amino-terminus. It is expressed in small intestine, colon, prostate, and human brain tissues, and the cGKII gene maps to chromosome 4q13.1-q21.1. cGKII has been shown to regulate the ion transport system in the intestine. Myristoylation of the penultimate glycine in cGKII appears to be essential for directing cGKII to the membrane, since cGKII is devoid of any hydrophobic transmembrane domains. The translocation of cGKII from the cytosol to the membrane allows it to function properly in regulating intestinal ion transport. | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | | Форма | Liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | Antigen affinity purification | | Области исследований | Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA962825(PRKG2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ?200)
 | The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA962825(PRKG2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ?200)
 | Gel: 8%SDS-PAGE, Lysate: 50 ?g, Lane 1-2: Mouse brain tissue, Mouse lung tissue, Primary antibody: CSB-PA962825(PRKG2 Antibody) at dilution 1/160, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds
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Наименование: PRKG2 Antibody.