Объем | 50 мкг |
Синонимы | Prospero homeobox protein 1 (Homeobox prospero-like protein PROX1) (PROX-1), PROX1 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q92786 |
Иммуноген | Recombinant Human Prospero homeobox protein 1 protein (262-477AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB, Recommended dilution: WB:1:500-1:5000 |
Примечание | Transcription factor involved in developmental processes such as cell fate determination, gene transcriptional regulation and progenitor cell regulation in a number of organs. Plays a critical role in embryonic development and functions as a key regulatory protein in neurogenesis and the development of the heart, eye lens, liver, pancreas and the lymphatic system. Involved in the regulation of the circadian rhythm. Represses: transcription of the retinoid-related orphan receptor RORG, transcriptional activator activity of RORA and RORG and the expression of RORA/G-target genes including core clock components: ARNTL/BMAL1, NPAS2 and CRY1 and metabolic genes: AVPR1A and ELOVL3. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | >95%, Protein G purified |
Абревеатура | Prospero homeobox protein 1 |
Области исследований | Epigenetics and Nuclear Signaling, Neuroscience, Cardiovascular, Signal transduction |
Ссылка на страницу на сайте производителя | ссылка |
Western Blot
Positive WB detected in: HepG2 whole cell lysate
All lanes: PROX1 antibody at 3µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 84 kDa
Observed band size: 84 kDa
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