Объем | 100 мкл |
Синонимы | Amyloid protein homolog , Amyloid-like protein 2 precursor, APP2, APPH, CDEI-box binding protein |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q06481 |
Иммуноген | Peptide sequence around phosphorylation site of tyrosine 755 (P-T-Y(p)-K-Y) derived from Human APLP2. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse, Rat |
Применение | ELISA, IHC,IHC:1:50-1:100 |
Примечание | <p>APLP2 May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). <br/><br/>Sprecher C.A., Biochemistry 32:4481-4486(1993).<br />Wasco W., Nat. Genet. 5:95-99(1993).<br />von der Kammer H., DNA Cell Biol. 13:1137-1143(1994).<br /></p> |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
Абревеатура | Phospho-Tyr755 |
Области исследований | Neuroscience |
Ссылка на страницу на сайте производителя | ссылка |
Immunohistochemical analysis of paraffin-embedded human brain tissue using APLP2 (Phospho-Tyr755) antibody (left)or the same antibody preincubated with blocking peptide (right).
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