PBX1 Antibody, Biotin conjugated

Спецификация

Объем	100 мкг
Синонимы	Pre-B-cell leukemia transcription factor 1 (Homeobox protein PBX1) (Homeobox protein PRL), PBX1, PRL
Клональность	Polyclonal Antibody
Организм	Human
uniprot	P40424
Иммуноген	Recombinant Human Pre-B-cell leukemia transcription factor 1 protein (315-430AA)
Источник	Rabbit
Видовая специфичность	Human
Применение	ELISA
Примечание	Binds the sequence 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. Converted into a potent transcriptional activator by the (1,19) translocation. May have a role in steroidogenesis and, subsequently, sexual development and differentiation. Isoform PBX1b as part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer, the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Probably in complex with MEIS2, is involved in transcriptional regulation by KLF4. Acts as a transcriptional activator of NKX2-5 and a transcriptional repressor of CDKN2B. Together with NKX2-5, it is required for spleen development through a mechanism that involves CDKN2B repression (By similarity).
Клональность1	Polyclonal
Изотип	IgG
Коньюгат	Biotin
Буффер	Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Форма	Liquid
Хранение	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Метод очистки	>95%, Protein G purified
Абревеатура	Pre-B-cell leukemia transcription factor 1
Области исследований	Epigenetics and Nuclear Signaling, Stem cells
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Информация для заказа

Область использования: Поликлональные антитела Cusabio	Производство:	Cusabio
	Метод:	Антитела
	Объем:	100 мкг
	Кат. номер:	CSB-PA017505LD01HU
Цена (с НДС 20%):	по запросу	В корзину
Наименование: PBX1 Antibody, Biotin conjugated. Примечание: дополнительная информация (на английском языке).