Объем | 50 мкг |
Синонимы | Polycomb group RING finger protein 6 (Mel18 and Bmi1-like RING finger) (RING finger protein 134), PCGF6, MBLR RNF134 |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q9BYE7 |
Иммуноген | Recombinant Human Polycomb group RING finger protein 6 protein (9-70AA) |
Источник | Rabbit |
Видовая специфичность | Human |
Применение | ELISA, WB, Recommended dilution: WB:1:500-1:5000 |
Примечание | Transcriptional repressor. May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Preservative: 0.03% Proclin 300<br />Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
Форма | Liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | >95%, Protein G purified |
Абревеатура | Polycomb group RING finger protein 6 |
Области исследований | Epigenetics and Nuclear Signaling |
Ссылка на страницу на сайте производителя | ссылка |
Western Blot
Positive WB detected in: PC-3 whole cell lysate, MCF-7 whole cell lysate
All lanes: PCGF6 antibody at 3.1µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 40, 31 kDa
Observed band size: 40 kDa
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