ATG4B AntibodyСпецификация| Объем | 100 мкл | | Синонимы | Cysteine protease ATG4B, EC 3.4.22.-, Autophagy-related protein 4 homolog B, hAPG4B, Autophagin-1 | | Клональность | Polyclonal Antibody | | Организм | Human | | uniprot | Q9Y4P1 | | Иммуноген | Synthesized peptide derived from internal of human ATG4B. | | Источник | Rabbit | | Видовая специфичность | Human, Mouse | | Применение | ELISA, WB, IHC,WB:1:500-1:3000, IHC:1:50-1:100 | | Примечание | Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.<br/><br/>Kabeya Y., J. Cell Sci. 117:2805-2812(2004).<br/>Marino G., J. Biol. Chem. 278:3671-3678(2003).<br/>Ota T.,Nat. Genet. 36:40-45(2004).<br/><br/> | | Клональность1 | Polyclonal | | Изотип | IgG | | Коньюгат | Non-conjugated | | Буффер | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. | | Форма | liquid | | Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | | Метод очистки | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | | Области исследований | Cancer,Cardiovascular,Cell biology,Metabolism,Signal transduction | | Ссылка на страницу на сайте производителя | ссылка | Western blot analysis of extracts from Jurkat cells, using ATG4B antibody.
 | Immunohistochemistry analysis of paraffin-embedded human skeletal muscle tissue using ATG4B antibody.
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Наименование: ATG4B Antibody.