| Объем | 100 мкл |
| Синонимы | Cytovillin, EZRI, VIL2, Villin 2, p81 |
| Клональность | Polyclonal Antibody |
| Организм | Human |
| uniprot | P15311 |
| Иммуноген | Peptide sequence around phosphorylation site of tyrosine 353 (Q-D-Y(p)-E-E) derived from Human EZRIN. |
| Источник | Rabbit |
| Видовая специфичность | Human, Mouse |
| Применение | ELISA, WB, IHC,WB:1:500-1:1000, IHC:1:50-1:100 |
| Примечание | <p>Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis. <br /><br />Zhao H, et al. (2004) Proc Natl Acad Sci U S A101 (25): 9485-9490. <br />Wang Q, et al. (2003) J Biol Chem 278(48): 47731-47743. <br />Gautreau A, et al. (1999) Proc Natl Acad Sci U S A 96(13): 7300-7305. <br />Crepaldi T, et al. (1997) J Cell Biol 138(2): 423-34. <br /> ,</p> |
| Клональность1 | Polyclonal |
| Изотип | IgG |
| Коньюгат | Non-conjugated |
| Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Форма | liquid |
| Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
| Абревеатура | Phospho-Tyr353 |
| Области исследований | Cancer,Signal transduction |
| Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from 293 cells untreated or treated with EGF using Ezrin(Phospho-Tyr353) Antibody.
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Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Ezrin(Phospho-Tyr353) Antibody(left) or the same antibody preincubated with blocking peptide(right).
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Наименование: Phospho-EZR (Tyr353) Antibody.