Объем | 100 мкл |
Синонимы | PBP, CRSP1, RB18A, TRIP2, PPARBP |
Клональность | Polyclonal Antibody |
Организм | Human |
uniprot | Q15648 |
Иммуноген | Peptide sequence around phosphorylation site of Threonine 1457(A-Y-T(p)-P-Q) derived from Human PPAR-BP. |
Источник | Rabbit |
Видовая специфичность | Human, Mouse |
Применение | ELISA, WB,WB:1:500-1:1000 |
Примечание | Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. |
Клональность1 | Polyclonal |
Изотип | IgG |
Коньюгат | Non-conjugated |
Буффер | Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Форма | liquid |
Хранение | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Метод очистки | Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide. |
Абревеатура | Phospho-Thr1457 |
Области исследований | Epigenetics and Nuclear Signaling,Cancer,Metabolism |
Ссылка на страницу на сайте производителя | ссылка |
Western blot analysis of extracts from HUVEC cells treated with serum using PPAR-BP (Phospho-Thr1457) Antibody.The lane on the left is treated with the antigen-specific peptide.
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